Sialic acid and cardiovascular mortality.

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Serum sialic acid concentration and cardiovascular mortality.

OBJECTIVE To determine whether serum sialic acid concentration may be used to predict short and long term cardiovascular mortality. DESIGN Prospective study on all men and women who had their serum sialic acid concentration measured as part of a general health survey in 1964 or in 1965. All were followed up for an average of 20.5 years. SETTING Geographical part of the county of Värmland, S...

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Serum Levels of Sialic Acid and Neuraminidase Activity in Cardiovascular, Diabetic and Diabetic Retinopathy Patients

Background: Sialic acid is a component of serum that is elevated in diseases such as diabetes and certain malignancies.  The normal range of SSA concentration and serum neuraminidase activity in different populations are varied, probably due to racial differences. Objective: The purpose of the present study was to obtain the average SSA concentration and serum neuraminidase activity, in an Iran...

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serum levels of sialic acid and neuraminidase activity in cardiovascular, diabetic and diabetic retinopathy patients

background: sialic acid is a component of serum that is elevated in diseases such as diabetes and certain malignancies.  the normal range of ssa concentration and serum neuraminidase activity in different populations are varied, probably due to racial differences.   objective: the purpose of the present study was to obtain the average ssa concentration and serum neuraminidase activity, in an ir...

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The role of sialic acid synthases in sialic acid biosynthesis

Introduction The sialic acids comprise a diverse family of nine-carbon keto-sugars, the majority of which are structural derivatives of neuraminic acid (Fig. 1). Neuraminic acid has an amino moiety at the C-5 position, and carboxylate at C-2 which confers negative charge at physiological pH. Whereas unsubstituted neuraminic acid is not known to exist in nature, over 40 substituted variations (c...

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Sialic acid and cell aggregation.

Chick embryo neural retina cells from 7-, 10and 14-day embryos and muscle cells from 9-day embryos, dissociated mechanically or with trypsin, reaggregate at the same initial rate whether treated before and during aggregation with active or inactive iV-acetyl neuraminidase. 7V-acetyl neuraminidase treatment also has no effect on the size or number of aggregates formed over 24 or 48 h of aggregat...

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ژورنال

عنوان ژورنال: BMJ

سال: 1991

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.302.6785.1154